Tumor Resistance Explained by Hormesis
نویسندگان
چکیده
منابع مشابه
Tumor resistance explained by hormesis.
Enhanced drug (GDC 0449) resistance in a mouse model for human medulloblastoma is shown in the present paper to act via an hormetic response. This has significant implications, imposing constraints on the quantitative features of the dose response of the chemotherapeutic agent, affecting optimal study design, mechanism assessment strategy, potential for tumor rebound, patient relapse and diseas...
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ژورنال
عنوان ژورنال: Dose-Response
سال: 2010
ISSN: 1559-3258,1559-3258
DOI: 10.2203/dose-response.09-063.calabrese